PRP (platelet-rich plasma) therapy for hair loss is a three-step medical treatment in which a person’s blood is drawn, processed, and then injected into the scalp.

Some in the medical community think that PRP injections trigger natural hair growth and maintain it by increasing blood supply to the hair follicle and increasing the thickness of the hair shaft. Sometimes this approach combine with other hair loss procedures or medications.

There hasn’t been enough research to prove if PRP is an effective hair loss treatment. However, PRP therapy has been in use since the 1980s. It’s been used for problems such as healing injured tendons, ligaments, and muscles.

PRP therapy process

PRP therapy is a three-step process. Most PRP therapy requires three treatments 4–6 weeks apart.

Maintenance treatments requir every 4–6 months.

Step 1

Your blood is drawn — typically from your arm — and put into a centrifuge (a machine that spins rapidly to separate fluids of different densities).

Step 2

After about 10 minutes in the centrifuge, your blood will have separated into in three layers:

  • platelet-poor plasma
  • platelet-rich plasma
  • red blood cells

Step 3

The platelet-rich plasma is drawn up into a syringe and then injected into areas of the scalp that need increased hair growth.

There hasn’t been enough research to prove whether PRP is effective. It’s also unclear for whom — and under what circumstances — it’s most effective.

According to a recent study, “Although PRP has sufficient theoretical scientific basis to support its use in hair restoration, hair restoration using PRP is still at its infancy. Clinical evidence is still weak.”

PRP for hair loss side effects

Because PRP therapy involves injecting your own blood into your scalp, you aren’t at risk for getting a communicable disease.

Still, any therapy that involves injections always carries a risk of side effects such as:

  • injury to blood vessels or nerves
  • infection
  • calcification at the injection points
  • scar tissue

There’s also the chance that you could have a negative reaction to the anesthetic used in the therapy. If you decide to pursue PRP therapy for hair loss, let your doctor know in advance about your tolerance to anesthetics.

What is PRP therapy ?

Risks of PRP for hair loss

Be sure to report all medications you’re on before the procedure including supplements and herbs.

When you go for your initial consultation, many providers will recommend against PRP for hair loss if you:

  • are on blood thinners
  • are a heavy smoker
  • have a history of alcohol or drug misuse

You might also reject for treatment if you’ve been diagnosed with:

  • acute or chronic infections
  • cancer
  • chronic liver disease
  • chronic skin disease
  • hemodynamic instability
  • hypofibrinogenemia
  • metabolic disorder
  • platelet dysfunction syndromes
  • systemic disorder
  • sepsis
  • low platelet count
  • thyroid disease

APPE is a mixture of refined growth factors extracted from human adipose-derived stem cells conditioned media and induces proliferation of dermal papilla cells of human hair follicles.